Neuropsychological effects of GPi deep brain stimulation in medication resistant dystonia

Date:

Deep brain stimulation (DBS) of the globus pallidus interna (GPi) is a treatment option for dystonia, but its effects on neuropsychological functions are not well understood. This poster examines whether DBS affects thinking and mood in patients with treatment-resistant dystonia by analyzing pre- and post-surgery neuropsychological test results. We found no significant changes in depression, anxiety, memory, attention, or other cognitive functions after surgery. These results suggest that GPi DBS is a safe treatment for treatment-resistant dystonia without negative effects on mental functions.

Recommended citation: Bishay AE, Tay A, Habib DRS, Qian H, Ball TJ, Englot DJ, Dhima K, Bick SK. Neuropsychological effects of GPi deep brain stimulation in medication resistant dystonia. Poster presented at: American Association of Neurological Surgeons Annual Meeting; April 25, 2025; Boston, MA, USA.